These doctor told my uncle to drinking so much wine if he wanted to be healthier.A. open

问题补充：

These doctor told my uncle to drinking so much wine if he wanted to be healthier.

A. open up

B. put up

C. give up

D. make up

答案：

A. open up

B. put up

(答案→)C. give up

D. make up

解析：open up打开，开发；put up提供，建造；give up放弃，交出； make up弥补，组成。句意：医生告诉我的叔叔，如果他想更健康一点，就要放弃和如此多的酒。故选C。